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A head shot photo of Jimmy Van Hear

Jimmy Van Hear

I am interested in understanding the role of mechanical properties in colorectal cancer (CRC). Using 3D organoid culture and a number of interdisciplinary imaging, molecular and modelling techniques, I hope to understand more about the mechanical and molecular environment involved in driving CRC development, and how physiological processes like cellular extrusion and wound healing can influence cancer progression.

Research themes


Polarity/cell shape

Signaling pathways

Cell-cell interactions

Cancer Mechanobiology

Light microscopy

High throughput screening


Organoid Culture


2019-2023  PhD Molecular Biology / Biophysics, University College London

2018-2019  Research technician

2013-2017   MSci, University of Birmingham


2024             Medical Research Council

2021              Medical Research Council

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